An analysis of the medical use of amphetamines during the 195060s

Im not sure if this is a medical use but one thing is sunflower oil. Are there any medical uses for cocaine? Cocaine is the original and still best local anesthetic.

An analysis of the medical use of amphetamines during the 195060s

This article has been cited by other articles in PMC. Abstract Amphetamine was discovered over years ago. Since then, it has transformed from a drug that was freely available without prescription as a panacea for a broad range of disorders into a highly restricted Controlled Drug with therapeutic applications restricted to attention deficit hyperactivity disorder ADHD and narcolepsy.

This review describes the relationship between chemical structure and pharmacology of amphetamine and its congeners. The review charts advances in pharmaceutical development from the introduction of once-daily formulations of amphetamine through to lisdexamfetamine, which is the first d-amphetamine prodrug approved for the management of ADHD in children, adolescents and adults.

An analysis of the medical use of amphetamines during the 195060s

The unusual metabolic route for lisdexamfetamine to deliver d-amphetamine makes an important contribution to its pharmacology. Alles, whilst he was searching for a less costly and more easily synthesised substitute for ephedrine.

It is the reason why the name Benzedrine, not amphetamine, appears in all of the early publications see Bett, Smith, Kline and French introduced Benzedrine onto the market in as a treatment for narcolepsy for which it is still used todaymild depression, post-encephalitic Parkinsonism and a raft of other disorders see Bett, ; Guttmann and Sargent, ; Tidy, As a molecule with a single chiral centre, amphetamine exists in two optically active forms, i.

Sales of Benzedrine and Dexedrine in chemist stores were unrestricted untilwhen these drugs could only be obtained either on prescription from a registered medical practitioner or by signing the Poison Register Bett, The cognitive-enhancing properties of amphetamine were quickly recognised, with reports of Benzedrine producing improvements in intelligence tests leading to its widespread use to reduce stress and improve concentration and intellectual performance by academics, students and medical professionals see Guttmann and Sargent, ; Tidy, In spite of considerable coverage in the medical literature and the popular press describing the powerful central effects of these new drugs, the addictive potential of amphetamine was largely dismissed see Bett, ; Guttmann and Sargent, ; Tidy, This chapter reviews the medical uses which gained the most acceptance, even though most of these are no longer current, such as amphetamine's use as decongestant, and treatment for narcolepsy, depression, and ADHD.

Chapter 3 Medical uses of amphetamines; Chapter 4 Amphetamines as performance enhancers; Chapter 5 Illicit amphetamine use. 1. A patient who has been using an amphetamine or a similar substance heavily and for a long time suddenly stops or markedly reduces its intake.

2. Within a few hours to several days of reducing intake, the patient develops dysphoric mood AND two or more of the following: 1. Fatigue 2. Unpleasant, vivid dreams 3. Excessive sleepiness or sleeplessness 4.

Jul 29,  · The objective of this study was to identify high-yield screening risk factors for detecting maternal non-medical drug use during pregnancy. A four year retrospective analysis was conducted at an academic medical center. According to the US National Library of Medicine, Amphetamines would not be used in pharmaceutical drugs or for medical purposes until the ’s when the drug was first noticed to dilate the bronchial sacs of the lungs and clear breathing passages for those who suffer from asthma, hay fever or the common cold.

By , the Benzedrine Inhaler was introduced on the market for use and quickly. a. Amphetamines can damage blood vessels in the brain, causing stroke.

b. Withdrawal from amphetamines is relatively brief, with no reports of discomfort or psychotic episodes within three days of stopping use. c. Tolerance of amphetamines builds slowly, if at all. d.

An analysis of the medical use of amphetamines during the 195060s

Most people who are treated for amphetamine abuse also abuse another substance. Amphetamine (alpha-methyl-phenethylamine), is a synthetic central nervous system stimulant which is used, today, to treat a very limited spectrum of medical disorders.


These include narcolepsy, refractory cases of attention-deficit hyperactivity disorder, and traumatic brain injury (where it is used to improve consciousness). Narcolepsy is a rare disorder, and the use of amphetamines in.

History of Amphetamines